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. 2020 Mar 26;21(7):2308. doi: 10.3390/ijms21072308

Figure 2.

Figure 2

Violin plots showing the distributions of (a) minor allele counts and (b) minor allele frequencies in 11 DPWG genes (CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A5, DPYD, F5, SLCO1B1, TPMT, UGT1A1, VKORC1) and an HLA-B*5701 tagging variant in gnomAD exomes v2.1.1, gnomAD genomes v3, and our in-house WGS cohort. Horizontal lines indicate median, horizontal dashed lines indicate quartiles. Plots were generated using Graphpad Prism 8 (Graphpad Software, CA, USA). Abbreviations: DPWG, Dutch Pharmacogenetics Working Group; LOF, loss of function.