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. 2020 Mar 24;92(8):5750–5755. doi: 10.1021/acs.analchem.9b05043

Figure 1.

Figure 1

(A) Schematics of on-chip hydrogel post synthesis for multiplexing of small miRNA panels using projection lithography with the spatial encoding scheme. (B) miRNA assay scheme: target hybridization, universal linker ligation, gold nanoparticle labeling, and gold ion deposition-based signal amplification. (C) Dark-field images of posts after complete miRNA assay demonstrating the dose-dependent response of miRNAs. Scale bar represents 100 μm.