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. 2019 Dec 20;36(8):2500–2505. doi: 10.1093/bioinformatics/btz944

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© The Author(s) 2019. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4. — An illustration of the heatmap produced by PheGWAS (single chromosomal view for 19th chromosome). The highlighted regions represent the SNPs with significant −log₁₀(p). This helps the user to decide which all chromosomes will be selected for the individual level chromosomal view. (A) rs2075650 found to be significantly associated (P-value: 9.7e-26) with HDL (SNPS in LD:NA). (B) rs7254892 found to be significantly associated (P-value: 1.6e-320) with LDL (SNPS in LD: rs3208856, rs283813, rs61679753, rs7412, rs75627662, rs445925). (C) rs7412 found to be significantly associated (P-value: 1.6e-283) with TOTAL CHOLESTROL (SNPS in LD: rs6859, rs7254892, rs61679753, rs405509, rs445925). (D) rs439401 found to be significantly associated (P-value: 1.4e-66) with TRIGS (SNPS in LD: rs75627662, rs445925