Table 4.
Diagnostic performance of RTE, TI-RADS, or both in 1525 nodules.
| Size interval (cm) | AUC (95%CI) | Sensitivity (%) | Specificity (%) | Accuracy (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|
| 0 < D ≤ 0.5 | ||||||
| TI-RADS | 0.916 (0.815–1.000) | 89.7 | 87.5 | 91.89 | 91.94 | 91.67 |
| RTE | 0.832 (0.714–0.950) | 74.1 | 81.2 | 75.67 | 93.48 | 46.43 |
| TI-RADS plus RTE | 0.941 (0.861–1.000) | 94.8 | 87.5 | 93.24 | 96.49 | 82.35 |
| 0.5 < D ≤ 1.0 | ||||||
| TI-RADS | 0.903 (0.871–0.935) | 87.9 | 85.3 | 89.20 | 87.03 | 94.30 |
| RTE | 0.943 (0.920–0.966) | 90.0 | 93.9 | 91.48 | 96.13 | 84.86 |
| TI-RADS plus RTE | 0.961 (0.941–0.982) | 90.0 | 93.9 | 91.29 | 97.03 | 83.56 |
| 1.0 < D ≤ 2.0 | ||||||
| TI-RADS | 0.894 (0.869–0.919) | 85.0 | 88.1 | 83.08 | 73.11 | 93.02 |
| RTE | 0.954 (0.937–0.970) | 94.1 | 94.4 | 94.27 | 91.81 | 95.97 |
| TI-RADS plus RTE | 0.972 (0.960–0.985) | 94.3 | 95.6 | 94.41 | 92.12 | 95.98 |
| 2.0 < D ≤ 2.5 | ||||||
| TI-RADS | 0.942 (0.912–0.973) | 86.3 | 92.9 | 88.94 | 94.69 | 82.11 |
| RTE | 0.919 (0.881–0.956) | 79.0 | 96.4 | 86.06 | 97.03 | 75.70 |
| TI-RADS plus RTE | 0.971 (0.951–0.990) | 89.5 | 95.2 | 91.83 | 96.52 | 86.02 |
Note. Unless otherwise indicated, the data point is percentage, and the number in parentheses is 95% CI. PPV = positive predictive value; NPV = negative predictive value.