Table 4.
Administration of co-analgesics and adjuvants.
| Immediately prior to tapentadol treatment | At the start of tapentadol treatment | At the end of observation | |
|---|---|---|---|
| Patients aged >65 years (n = 752) | |||
| Co-analgesics | 299 (39.8%) | 275 (36.6%) | 249 (33.1%) |
| Antidepressants | 229 (30.5%) | 219 (29.1%) | 205 (27.3%) |
| Antiepileptics | 121 (16.1%) | 97 (12.9%) | 79 (10.5%) |
| No data | 0 | 0 | 30 (4%) |
| Adjuvants | 221 (29.4%) | 197 (26.2%) | 152 (20.2%) |
| Antiemetics | 83 (11%) | 70 (9.3%) | 49 (6.5%) |
| Laxatives | 170 (22.6%) | 144 (19.2%) | 120 (16%) |
| Adjuvants NOS | 1 (0.1%) | 2 (0.3%) | 0 |
| No data | 3 (0.4%) | 3 (0.4%) | 38 (5.1%) |
| Rescue medication | 256 (34%) | 235 (31.3%) | 212 (28.2%) |
| No data | 4 (0.5%) | 2 (0.3%) | 39 (5.2%) |
| Patients aged ≤65 years (n = 282) | |||
| Co-analgesics | 133 (47.2%) | 110 (39%) | 92 (32.6%) |
| Antidepressants | 111 (39.4%) | 99 (35.1%) | 81 (28.7%) |
| Antiepileptics | 54 (19.2%) | 36 (12.8%) | 30 (10.6%) |
| No data | 0 | 0 | 8 (2.8%) |
| Adjuvants | 67 (23.8%) | 53 (18.8%) | 28 (9.9%) |
| Antiemetics | 36 (12.8%) | 28 (9.9%) | 15 (5.3%) |
| Laxatives | 45 (16%) | 33 (11.7%) | 20 (7.1%) |
| Adjuvants NOS | 1 (0.4%) | 1 (0.4%) | 0 |
| No data | 1 (0.4%) | 2 (0.7%) | 13 (4.6%) |
| Rescue medication | 76 (27%) | 74 (26.2%) | 70 (24.8%) |
| No data | 2 (0.6%) | 1 (0.4%) | 10 (3.6%) |
NOS, not otherwise specified. Data are number of patients (%).