Table 3.
Hematologic, serum ferritin, and serum iron characterization between −α3.7 genotypes and gender from the first-time blood donors from FHEMOAM (2016-2017).
Parameters data | α-Globin genotypes (all) | p value | α-Globin genotypes (male) | p value | α-Globin genotypes (female) | p value | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
αα/αα | −α3.7/αα | α 3.7/α3.7 | αα/αα | −α3.7/αα | α 3.7/α3.7 | αα/αα | −α3.7/αα | α 3.7/α3.7 | ||||
WBC (×103/μL) | 6.92 ± .96 | 7.21 ± .68 | 7.16 ± 1.11 | 0.174 | 6.99 ± .95 | 7.33 ± .63 | 7.19 ± 1.57 | 0.179 | 6.68 ± .96 | 6.84 ± .73 | 7.11 ± .88 | 0.802 |
RBC (×106/mm L) | 4.74 ± .43 | 5.04 ± .35 | 5.57 ± .76 | <0.001 | 4.87 ± .38 | 5.11 ± .32 | 5.76 ± .73 | <0.001 | 4.42 ± .36 | 4.77 ± .31 | 5.09 ± .35 | <0.001 |
Hg (g/dL) | 14.13 ± 1.28 | 14.05 ± 1.41 | 12.11 ± 1.38 | <0.001 | 14.60 ± 1.1 | 14.47 ± 1.2 | 12.54 ± 1.4 | <0.001 | 12.99 ± 1.1 | 12.35 ± .7 | 11.05 ± .91 | 0.009 |
Hct (%) | 43.21 ± 3.32 | 43.13 ± 3.03 | 42.01 ± 2.66 | .591 | 44.26 ± 2.9 | 43.81 ± 2.7 | 42.58 ± 2.5 | 0.292 | 40.32 ± 2.7 | 39.51 ± 2.1 | 39.1 ± 1.9 | 0.659 |
MCV (fL) | 90.39 ± 4.42 | 84.97 ± 4.81 | 74.49 ± 7.28 | <0.001 | 90.91 ± 4.41 | 85.83 ± 4.70 | 74.54 ± 2.89 | <0.001 | 89.12 ± 4.2 | 81.41 ± 3.6 | 73.59 ± .5 | <0.001 |
MCH (pg/l) | 29.82 ± 1.82 | 27.87 ± 2.34 | 21.98 ± 3.09 | <0.001 | 29.99 ± 1.7 | 28.34 ± 2.2 | 22.09 ± 3.7 | <0.001 | 29.42 ± 1.9 | 25.93 ± 1.7 | 21.69 ± .29 | <0.001 |
MCHC (g/dl) | 32.96 ± 1.08 | 32.77 ± 1.42 | 29.43 ± 1.82 | <0.001 | 32.99 ± 1.44 | 33.01 ± 1.43 | 29.40 ± 2.21 | <0.001 | 32.89 ± 1.2 | 31.83 ± 1.1 | 29.48 ± .61 | <0.001 |
RDW (%) | 13.27 ± .89 | 14.59 ± 1.23 | 16.13 ± 1.51 | <0.001 | 12.43 ± .91 | 13.85 ± 1.2 | 16.18 ± 1.4 | <0.001 | 12.88 ± .72 | 13.52 ± .54 | 15.11 ± 2.3 | <0.001 |
Platelet (×109/L) | 278.3 ± 98.8 | 261.6 ± 61.8 | 277.4 ± 92.8 | 0.461 | 272.2 ± 87.4 | 261.3 ± 72.4 | 257.4 ± 124.5 | 0.709 | 293.3 ± 106.6 | 263.1 ± 54.9 | 281.7 ± 38.2 | 0.693 |
Serum iron (μg/dL) | 91.29 ± 19.31 | 82.15 ± 102.4 | 60.29 ± 28.2 | <0.001 | 81.9 ± 5.5 | 76.6 ± 4.5 | 51.2 ± 27.5 | <0.001 | 120.6 ± 17.5 | 99.5 ± 30.8 | 78.5 ± 26.4 | <0.001 |
Serum ferritin (μg/dL) | 156.1 ± 47.7 | 157.4 ± 45.9 | 118.2 ± 59.66 | <0.001 | 179.1 ± 28.1 | 169.8 ± 21.4 | 121.12 ± 79.7 | <0.001 | 88.1 ± 22.6 | 87.5 ± 26.1 | 84.4 ± 24.4 | .894 |