Table 1.
The Chiu's core classification of small intestine injury.
| Classification | Pathological change |
|---|---|
| Level 0 | Mucosa without changes. |
| Level 1 | Well-constituted villosities, no cellular lysis or inflammatory process, although there is formation of Grunhagen's sub-epithelial space. |
| Level 2 | Presence of cellular lysis, formation of Grunhagen's sub-epithelial space and increased spacing among the villosities. |
| Level 3 | Destruction of the free villosities section, presence of dilated capillaries and inflamed cells. |
| Level 4 | Structural destruction of the villosities, only traces of some villosities, formed by inflamed cells and necrotic material, with hemorrhage and basal glandular ulceration. |
| Level 5 | Destruction of all the mucosa, no glandular structure can be seen, only the amorphous material laying on the sub-mucosa tissue. |