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. 2020 Apr 10;32:101534. doi: 10.1016/j.redox.2020.101534

Table 1.

The Chiu's core classification of small intestine injury.

Classification Pathological change
Level 0 Mucosa without changes.
Level 1 Well-constituted villosities, no cellular lysis or inflammatory process, although there is formation of Grunhagen's sub-epithelial space.
Level 2 Presence of cellular lysis, formation of Grunhagen's sub-epithelial space and increased spacing among the villosities.
Level 3 Destruction of the free villosities section, presence of dilated capillaries and inflamed cells.
Level 4 Structural destruction of the villosities, only traces of some villosities, formed by inflamed cells and necrotic material, with hemorrhage and basal glandular ulceration.
Level 5 Destruction of all the mucosa, no glandular structure can be seen, only the amorphous material laying on the sub-mucosa tissue.