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. 2020 Apr 22;20:299. doi: 10.1186/s12879-020-05024-4

Table 2.

Patterns of SDU and perceptions related PrEP among GBMSM with experience of SDU in the past year

% / Mean (SD)
Patterns of SDU (n = 82)
Types of psychoactive substance used during SDU in past year
 Ketamine 1.2
 Methamphetamine 31.7
 Cocaine 1.2
 Cannabis 8.5
 Ecstasy 3.7
 Dormicum / Halcion / Erimin 5 / Hypnotic drugs (non-prescription) 0.0
 Heroin 0.0
 Cough suppressant (not for curing cough) 1.2
 Amyl nitrite 80.5
 GHB/GBL 31.7
 5-methoxy-N, N-diisopropyltryptamine (Foxy) 4.9
 Mephedrone 0.0
Poly-use of psychoactive substances in lifetime
 No 69.5
 Yes 30.5
Time since the first episode of SDU
  < 1 year 40.2
 1–2 years 15.9
 3–5 years 15.9
  > 5 years 28.0
Frequency of SDU in the past year
 1 episode/month 37.8
 1–2 episodes/month 29.3
  ≥ 3 episodes/month 32.9
Condomless anal intercourse during SDU in the past year
 No 48.8
 Yes 51.2
Drug cessation/rehabilitation services provided by governmental organizations
 No 97.6
 Yes 2.4
Drug cessation/rehabilitation services provided by non-governmental organizations
 No 90.2
 Yes 9.8
Details of the most recent episode of SDU
 Number of participants
  2 78.0
   ≥ 3 22.0
 Alcohol consumption
  No 85.4
  Yes 14.6
 Use of erectile dysfunction drugs
  No 69.5
  Yes 30.5
 Group sex
  No 80.5
  Yes 19.5
 Condomless anal intercourse
  No 48.8
  Yes 51.2
Perceptions related to PrEP (among participants with experience of SDU in the past year who were not on PrEP) (n = 70)
Willingness to take once-daily oral pill as PrEP in the next six months after being briefed some facts of PrEP
 No (definitely not/probably not/neutral) 32.9
 Yes (probably will/definitely will) 67.1
Willingness to pay (HK$ per month) for using once-daily oral pill as PrEP (among those with willingness to take PrEP in the next six months, n = 56)
  ≤ 300 24.2
 301–500 14.3
 501–1000 18.6
 1000–2000 21.4
 2001–4000 17.1
 4001–6000 2.9
 6001–8000 1.4
  > 8000 0.0
Perceptions related to PrEP based on the TPB
 Positive attitudes toward PrEP (% agree)
  PrEP can reduce your chance of HIV infection during SDU 81.4
  PrEP would reduce your worry of HIV infection when having condomless sex during SDU 64.3
  PrEP provides you more choice for HIV prevention 84.3
Positive Attitude Scalea 8.1 (1.3)
 Negative attitudes toward PrEP (% agree)
  Psychoactive substances that are used during SDU would reduce the protective effect of PrEP 17.1
  Psychoactive substances that are used during SDU would aggravate the side-effects of PrEP 30.0
  Psychoactive substances that are used during SDU would make you forget to take PrEP 28.6
  Daily use of PrEP would cause severe financial burden for you 80.0
  You will be stigmatized by medical professionals when you are using PrEP-related services 37.1
Negative Attitude Scaleb 10.2 (2.2)
 Perceived subjective norm related to PrEP
  People who are important to you will support you to use PrEP
   Disagree/neutral 32.9
   Agree 67.1
 Perceived behavioral control to use PrEP
  In general, you are confident in taking PrEP every day in the next six months
  Strongly disagree/disagree/neutral 35.7
  Agree/strongly agree 64.3

Sexualized drug use is defined as use of the following psychoactive substances before/during anal intercourse, including ketamine, methamphetamine, cocaine, cannabis, ecstasy, Dormicum/Halcion/Erimin 5/non-prescription hypnotic drugs, heroin, cough suppressant (not for curing cough), amyl nitrite (popper), GHB/GBL (γ-hydroxybutyrate), 5-methoxy-N, N-diisopropyltryptamine (Foxy), and mephedrone

aPositive Attitude Scale, three items, Cronbach’s alpha: 0.648, one factor was identified by explanatory factor analysis, explaining for 61.6% of the total variance. Higher score of the scale indicated more positive attitudes toward PrEP

bNegative Attitude Scale, five items, Cronbach’s alpha: 0.747, one factor was identified by explanatory factor analysis, explaining for 56.6% of the total variance. Higher score of the scale indicated more negative attitudes toward PrEP