Table 2.
Susceptibility indices and allelic and homozygous percentages of mutations in the voltage-gated sodium channels in Aedes aegypti in Nepal
| Collection sitea | Latitude | Longitude | Susceptibility index | Frequency (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L1014F | V1016G | F1534C | ||||||||||
| n | Allelic % | Homozygous % | n | Allelic % | Homozygous % | n | Allelic % | Homozygous % | ||||
| BAR001 | 27.63 | 84.50 | 4 | 3 | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 0 |
| BAR002 | 27.62 | 84.54 | 3 | 13 | 0 | 0 | 17 | 0 | 0 | 17 | 0 | 0 |
| BAR004 | 27.61 | 84.60 | 18 | 6 | 0 | 0 | 7 | 7.1 | 0 | 19 | 2.6 | 0 |
| BAR005 | 27.60 | 84.64 | 3 | 4 | 0 | 0 | 4 | 0 | 0 | 9 | 0 | 0 |
| BAR006 | 27.60 | 84.68 | 30 | 3 | 0 | 0 | 3 | 33.3 | 33.3 | 4 | 12.5 | 0 |
| BAR007 | 27.58 | 84.73 | 18 | 12 | 0 | 0 | 13 | 15.4 | 7.7 | 13 | 0 | 0 |
| BAR008 | 27.54 | 84.79 | 12 | 3 | 0 | 0 | 3 | 0 | 0 | 5 | 0 | 0 |
| BAR009 | 27.53 | 84.81 | 5 | 13 | 0 | 0 | 16 | 0 | 0 | 18 | 0 | 0 |
| BAR015 | 27.62 | 84.51 | 36 | 7 | 0 | 0 | 11 | 0 | 0 | 15 | 0 | 0 |
| BAR018 | 27.73 | 84.45 | – | 3 | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 0 |
| BAR019 | 27.70 | 84.43 | 6 | 2 | 0 | 0 | 7 | 0 | 0 | 7 | 7.1 | 0 |
| BAR020 | 27.70 | 84.42 | 15 | 6 | 0 | 0 | 13 | 0 | 0 | 12 | 4.2 | 0 |
| BAR021 | 27.69 | 84.41 | 18 | 5 | 0 | 0 | 15 | 16.7 | 6.7 | 12 | 0 | 0 |
| BAR022 | 27.69 | 84.42 | 36 | 9 | 0 | 0 | 16 | 34.4 | 18.8 | 15 | 0 | 0 |
| KTM003 | 27.71 | 85.35 | 12 | 6 | 0 | 0 | 10 | 50.0 | 40.0 | 12 | 4.2 | 0 |
| KTM004 | 27.67 | 85.34 | 12 | 1 | 0 | 0 | 7 | 42.9 | 14.3 | 6 | 0 | 0 |
| KTM005 | 27.67 | 85.32 | 18 | 5 | 0 | 0 | 12 | 29.2 | 0 | 10 | 10.0 | 0 |
| KTM006 | 27.75 | 85.35 | 36 | 2 | 0 | 0 | 12 | 70.8 | 41.7 | 13 | 0 | 0 |
| KTM008 | 27.73 | 85.31 | 30 | 7 | 0 | 0 | 13 | 69.2 | 46.2 | 17 | 0 | 0 |
| KTM009 | 27.73 | 85.31 | 18 | 5 | 0 | 0 | 10 | 40.0 | 10.0 | 14 | 7.2 | 0 |
| KTM010 | 27.72 | 85.29 | 6 | na | na | na | na | na | na | 1 | 0 | 0 |
| KTM011 | 27.71 | 85.28 | 36 | 1 | 0 | 0 | 4 | 25.0 | 0 | na | na | na |
| PKR002 | 28.21 | 83.98 | 36 | 20 | 0 | 0 | 19 | 39.5 | 26.3 | 9 | 66.7 | 66.7 |
| PKR003 | 28.22 | 83.98 | 36 | 16 | 0 | 0 | 16 | 28.1 | 0 | 6 | 16.7 | 0 |
| PKR004 | 28.20 | 84.00 | 18 | 8 | 0 | 0 | 8 | 50.0 | 25.0 | 5 | 30.0 | 0 |
| PKR005 | 28.20 | 84.01 | 12 | 5 | 0 | 0 | 6 | 16.7 | 0 | 7 | 0 | 0 |
| PKR006 | 28.20 | 84.01 | 18 | 18 | 0 | 0 | 18 | 8.3 | 0 | 17 | 11.8 | 0 |
| PKR007 | 28.20 | 84.02 | 18 | 8 | 0 | 0 | 8 | 6.3 | 0 | 6 | 25.0 | 0 |
| PKR008 | 28.20 | 84.02 | 36 | 13 | 0 | 0 | 13 | 26.9 | 15.4 | 5 | 0 | 0 |
| PKR009 | 28.21 | 83.99 | 18 | 12 | 0 | 0 | 11 | 31.8 | 27.3 | 6 | 25.0 | 0 |
| PKR010 | 28.23 | 83.98 | 18 | 4 | 0 | 0 | 3 | 50.0 | 33.3 | 3 | 0 | 0 |
| PKR012 | 28.21 | 83.98 | 30 | 3 | 0 | 0 | 5 | 70.0 | 60.0 | 5 | 0 | 0 |
| PKR013 | 28.21 | 83.98 | 30 | 5 | 0 | 0 | 5 | 40.0 | 20.0 | 4 | 0 | 0 |
aLarvae were collected from 20–24 August 2017 at Kathmandu (KTM) and Bharatpur (BAR), and from 12–13 September 2018 in Pokhara (PKR)
Abbreviation: na, not available