Table 1.
Clinical characteristics of prostate cancer patients
| Features | PSA | P value | |||
|---|---|---|---|---|---|
| < 4 | 4–10 | 10–20 | > 20 | ||
| Age | |||||
| < 65 | 13,817 (57.4) | 63,034 (49.8) | 12,405 (38.7) | 8629 (37.3) | < 0.001 |
| ≥ 65 | 10,237 (42.6) | 63,629 (50.2) | 19,680 (61.3) | 14,482 (62.7) | |
| Married status | |||||
| Married | 16,661 (69.3) | 84,764 (66.9) | 19,799 (61.7) | 12,530 (54.2) | < 0.001 |
| Unmarried | 4388 (18.2) | 25,624 (20.2) | 8142 (25.4) | 7540 (32.6) | |
| Unknown | 3005 (12.5) | 16,275 (12.8) | 4144 (12.9) | 3041 (13.2) | |
| Insurance | |||||
| Insured | 21,608 (89.8) | 114,316 (90.3) | 28,918 (90.1) | 20,417 (88.3) | < 0.001 |
| Uninsured | 210 (0.9) | 1578 (1.2) | 606 (1.9) | 830 (3.6) | |
| Unknown | 2236 (9.3) | 10,769 (8.5) | 2561 (8.0) | 1864 (8.1) | |
| Race | |||||
| Caucasian | 19,460 (80.9) | 96,796 (76.4) | 23,140 (72.1) | 15,639 (67.7) | < 0.001 |
| African-American | 3066 (12.7) | 19,717 (15.6) | 5875 (18.3) | 5309 (23.0) | |
| Other | 801 (3.3) | 6578 (5.2) | 2210 (6.9) | 1619 (7.0) | |
| Unknown | 727 (3.0) | 3572 (2.8) | 860 (2.7) | 544 (2.4) | |
| T stage | |||||
| T1 | 8243 (34.3) | 56,428 (44.5) | 14,252 (44.4) | 8916 (38.6) | < 0.001 |
| T2 | 13,705 (57.0) | 56,084 (44.3) | 11,943 (37.2) | 7968 (34.5) | |
| T3 | 1803 (7.5) | 12,825 (10.1) | 5305 (16.5) | 4234 (18.3) | |
| T4 | 74 (0.3) | 270 (0.2) | 247 (0.8) | 1158 (5.0) | |
| Unknown | 229 (1.0) | 1056 (0.8) | 338 (1.1) | 835 (3.6) | |
| N stage | |||||
| N0 | 23,083 (96.0) | 121,322 (95.8) | 29,675 (92.5) | 17,942 (77.6) | < 0.001 |
| N1 | 266 (1.1) | 1565 (1.2) | 1287 (4.0) | 3374 (14.6) | |
| Unknown | 705 (2.9) | 3776 (3.0) | 1123 (3.5) | 1795 (7.8) | |
| M stage | |||||
| M0 | 23,847 (99.1) | 125,996 (99.5) | 31,213 (97.3) | 16,996 (73.5) | < 0.001 |
| M1 | 207 (0.9) | 667 (0.5) | 872 (2.7) | 6115 (26.5) | |
| Gleason grade | |||||
| 1 | 13,865 (57.6) | 58,851 (46.5) | 9635 (30.0) | 2548 (11.0) | < 0.001 |
| 2 | 6020 (25.0) | 37,375 (29.5) | 8660 (27.0) | 3712 (16.1) | |
| 3 | 1922 (8.0) | 15,144 (12.0) | 5403 (16.8) | 3649 (15.8) | |
| 4 | 1261 (5.2) | 9783 (7.7) | 4604 (14.3) | 5401 (23.4) | |
| 5 | 986 (4.1) | 5510 (4.4) | 3783 (11.8) | 7801 (33.8) | |
Abbreviations: PSA, prostate-specific antigen