. 2020 Apr 23;11:45. doi: 10.1186/s40104-020-00440-7

Table 3.

Effect of birth weight (n = 90), weaning treatment (n = 60) and days post-weaning (n = 36), and their interaction (n = 12-30), on the glutathione redox system in weaned piglets

	GSH, μmol/mg prot.				GSSG, μmol/mg prot.				GPx, U/g prot.				GST, U/g prot.
	ERY^§	DUO	JEJ	LIV	ERY^§	DUO	JEJ	LIV	PLA^†	DUO	JEJ	LIV	DUO	JEJ	LIV
Birth weight category (BiW)
LBW	955	22	15.6	46.9	60	0.71	0.35	0.85	0.286	8.9	8.6	31.8	28.1	10.9	78
NBW	989	21.9	16.1	43.6	65	0.72	0.38	0.8	0.292	8.7	8.7	31.8	29.6	10.4	76.6
Weaning treatment (WT)
3d3w	893^a	20.6^a	14.5^a	40.6	69	0.83^b	0.44^b	0.8	0.279	8.2^a	9.5	33.7^b	28.7	10.4	73.6^ab
3w	1010^b	22.1^ab	16.9^b	44	62	0.64^a	0.36^ab	0.78	0.285	9.6^b	8.1	31.4^ab	27.9	10.8	69.7^a
4w	1012^b	23.2^b	16.2^ab	51.2	56	0.68^ab	0.30^a	0.9	0.302	8.6^ab	8.4	30.3^a	29.9	10.7	88.6^b
Day post-weaning (DPW)
d 0	938^y	17.8^x	14.4^y	51.3	56	0.55^xy	0.35^yz	0.89^yz	0.235^x	8.2^yz	7.1^y	33.4^z	22.3^y	10.7^yz	81.5^yz
d 2	881^y	17.6^x	15.8^yz	39.9	57	0.38^x	0.26^y	0.73^y	0.280^xy	9.9^z	9.7^z	28.0^y	20.5^y	10.2^yz	56.0^x
d 5	842^y	22.1^y	16.3^yz	44.4	67	0.74^y	0.48^z	0.61^y	0.373^z	9.9^z	10.6^z	32.1^yz	26.5^y	8.2^y	67.9^xy
d 12	997^y	27.3^z	18.1^z	50.1	60	0.75^y	0.41^yz	0.73^y	0.304^y	8.7^yz	9.8^z	33.2^z	37.1^z	12.5^z	78.4^xy
d 28	1201^z	25.0^xy	14.0^yz	40.7	73	1.17^z	0.32^yz	1.17^z	0.253^x	7.3^y	6.3^y	32.4^yz	37.9^z	11.6^yz	102.8^z
SEM	21	0.4	0.4	2.4	2	0.03	0.02	0.05	0.005	0.2	0.3	0.5	1.1	0.4	2.7
P-value
BiW	0.416	0.850	0.616	0.499	0.353	0.882	0.502	0.565	0.615	0.758	0.892	0.998	0.474	0.544	0.798
WT	0.033	0.027	0.054	0.195	0.072	0.051	0.054	0.478	0.195	0.018	0.121	0.032	0.736	0.939	0.010
DPW	< 0.001	< 0.001	0.053	0.450	0.085	< 0.001	0.029	0.002	< 0.001	< 0.001	< 0.001	0.009	< 0.001	0.013	< 0.001
BiW×DPW	0.687	0.682	0.416	0.211	0.983	0.200	0.796	0.891	0.807	0.525	0.344	0.645	0.475	0.580	0.887
WT×DPW	< 0.001	0.067	0.026	0.276	0.143	< 0.001	< 0.001	0.001	0.040	0.325	0.738	0.049	0.039	0.012	0.874
BiW×WT	0.493	0.123	0.391	0.654	0.906	0.423	0.999	0.966	0.676	0.523	0.896	0.310	0.043	0.763	0.930

Birth weight (BiW), weaning treatment (WT), days post-weaning (DPW), glutathione (GSH), glutathione disulphide (GSSG), glutathione peroxidase (GPx), glutathione transferase (GST), duodenal mucosa (DUO), distal jejunal mucosa (JEJ), liver tissue (LIV). Piglets were either weaned at 3 weeks of age (3w), 4 weeks of age (4w), or separated from the sow at 3 d of age and fed a milk replacer until weaning at 3w of age (3d3w), and either had a low birth weight or normal birth weight (NBW). Values are least squares means. ^a,b Within a column, means without a common superscript differ for the effect of weaning treatment (WT: P ≤ 0.05). ^x,y,z Within a column, means without a common superscript differ for the effect of days post-weaning (DPW: P ≤ 0.05). ^§ Expressed in nmol/mL blood. † Expressed in U/mL blood plasma