Table 5.

Univariate and multivariate analyses of association of baseline prognostic factors with 5-year OS of patients with CRC

Variable	Univariate analysis		Multivariate analysis		P
	5 year-OS	P	HR	CL (95%)
Gender		0.231			NS
Female	82.8
Male	69.6
Age		0.256			NS
≥ 65	61.3
< 65	79.1
Location		0.166			NS
Colon	60.2
Rectum	73.7
T stage		0.000			0.029
T1-T2	90.0		1
T3-T4	49.8		8.905	1.256–63.182
N stage		0.004			NS
N0	81.1		1
N1-N2	50.0		6.225	0.454–85.377
M stage		0.000			NS
M0	78.1		1
M1	34.3		6.383	0.905–45.004
TNM stage		0.001			NS
I-II	86.9		1
III-IV	26.4		0.195	0.009–4.458
Histological grade		0.124			NS
Well	90.9
Moderately	72.7
Poorly	48.5
CEA		0.003			NS
≥ 5	34.3		1
< 5	76.7		1.344	0.269–6.711
CA19–9		0.117			NS
≥ 37	54.5
< 37	67.1
CIP2A		0.043			0.052
Low expression	75.4		1
High expression	57.4		4.301	0.988–18.725