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PPNPs/GEM treatment alters surface charge on PanCa cells. Zeta potential measurements were performed on whole cell suspension in PBS after 24 h treatment of PanCa cells with 10 nM PTX, 100 nM GEM, 10 nM PPNPs, and 10 nM PPNPs/100 nM GEM. No treatment and blank PLGA NPs served as the respective control groups. PPNPs/GEM exhibits neutralization of the negatively charged functional membrane. Data are represented as mean ± SEM (n = 3).
