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. 2020 Apr 16;9(1):1750810. doi: 10.1080/20013078.2020.1750810

Figure 1.

Figure 1.

Characterisation and quantification of EVs from different C. albicans strains. (a) Representative TEM images of EVs isolated from different C. albicans strains. Scale bar indicates 0.5 µm. (B) Size distribution of DAY286 yeast (n = 3), ATCC90028 yeast (n = 3), ATCC10231 yeast (n = 3), and DAY286 biofilm (n = 5) EVs as measured by nanoparticle tracking analysis. Bar plots show the percentage of the total number of EVs that can be assigned to each size range. The size of the bars indicates the mean percentage across each biological replicate and the error bars indicate the standard error of the mean. NTA traces for the individual biological replicates are presented in Supplementary Figure S2. (C) Comparison of the ratio of particle concentration to protein concentration of the EV fraction, (particles/mL) ÷ (µg protein/mL), across the four EV sources. Each dot represents one biological replicate. Sample means were compared using One-way ANOVA followed by Tukey’s HSD post-hoc test. Adjusted p-values indicating significant differences are shown. The particle and protein concentrations for each biological replicate are provided in Supplementary Table S1.