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Scheme of the potential of EVs in disease treatment and drug delivery. EVs can be isolated from different ‘factories’ (dendritic cells, mesenchymal stem cells, macrophages, milk, tumor cells, others), loading different cargos (small molecules, nucleic acids, protein, metal nanoparticles), and targeting to precise disease (cardiovascular disease, neurodegenerative disease, osteoporosis, cancer, malignancies, and metastasis).
