Table 5.

Results of ALDEx2 analysis comparing women with the combination of active decay and generalized gingivitis to those with neither*. Center for Oral Health Research in Appalachia Cohort 2 participants. Effect sizes of taxa with p values <0.02 at 2 or 12 months; those meeting this criterion are bolded. Negative values represent factors positively associated with active decay and gingivitis; positive values represent a negative association with active decay and gingivitis

	Effect Size
Taxa	2 months	12 months
Corynebacterium matruchotii	1.019	0.384
Fusobacterium nucleatum subsp. fusiforme	0.600	0.769
Fusobacterium nucleatum subsp. polymorphum	−0.826	−0.477
Haemophilus parainfluenzae	−1.253	−0.808
Haemophilus_18674	−0.687	−0.647
Haemophilus_19524	−0.941	−0.701
Haemophilus_nbw161b08c1	−1.043	−0.749
Lactobacillus fermentum	0.473	0.588
Neisseria meningitidis polysaccharea	−0.906	−0.835
Oribacterium sinus	−0.765	−0.872
Prevotella pleuritidis	0.891	0.898
Prevotella nigrescens	0.891	0.686
Prevotella_oral taxon 299	0.595	−0.834
Selenomonas noxia	0.962	0.700
Streptococcus peroris	0.481	0.666
Streptococcus_18830	0.740	0.767
Streptococcus_18832	0.733	0.724
Streptococcus_18846	0.772	0.739
Streptococcus_6815	0.711	0.689
Streptococcus_GU045364	0.734	0.765
unclassified Clostridiales C sulci infirmum	−0.892	−0.771
Veillonella atypica dispar parvula	0.631	−0.167
Veillonella_HB016	1.085	0.104

*12 with active decay and generalized gingivitis and 64 with neither at 2-month post-partum; 15 with active decay and generalized gingivitis and 51 with neither at 12-month post-partum.

Note: Taxa not identified to the species level are given an arbitrary number. These sequences were further identified using NCBI BLAST in Supplemental Table 2.