Figure 7.

Stress-induced decrease in GluA1-IR is prevented by a β-adrenergic receptor antagonist. A, The downregulation of GluA1-IR after stress was partially prevented by propranolol administration. B, Quantification of GluA1-IR in the molecular layer of lobule 5 from animals administered saline or propranolol before stress (naive, N = 5; saline, N = 5; propranolol, N = 5). The level of GluA1-IR was significantly higher in the molecular layer in the propranolol-administered animals compared with the saline-injected mice. Scale bar, 100 µm. *p < 0.002 (unpaired t test).