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. 2020 Apr 22;22:38. doi: 10.1186/s13058-020-01276-9

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — mRNA levels in various types of tumors and their corresponding normal tissue. The RPKM mRNASeq expression profiles are presented for each TCGA disease chart. The results are, in part, based upon the data generated by the TCGA Research Network: https://www.cancer.gov/tcga. This graphical presentation was obtained using the FireBrowse tool. The results for the following tissues (n = tumor samples; normal samples) are presented: BLCA, bladder urothelial carcinoma (n = 49; 11); BRCA, breast invasive carcinoma (n = 699; 88); COAD, colon adenocarcinoma (n = 10); COADREAD, colorectal adenocarcinoma (n = 75); ESCA, esophageal carcinoma (n = 185; 13); HNSC, head and neck squamous cell carcinoma (n = 236; 27); KIPAN, pan-kidney cohort (KICH+KIRC+KIRP) (n = 446; 68); KIRC, kidney renal clear cell carcinoma (n = 433; 68); KIRP, kidney renal papillary cell carcinoma (n = 13); LAML, acute myeloid leukemia (n = 176); LIHC, liver hepatocellular carcinoma (n = 17; 9); LUAD, lung adenocarcinoma (n = 120; 37); LUSC, lung squamous cell carcinoma (n = 212; 17); OV, ovarian serous cystadenocarcinoma (n = 299); READ, rectum adenocarcinoma (n = 65); STAD, stomach adenocarcinoma (n = 272; 33); STES, stomach and esophageal carcinoma (n = 457; 46); THCA, thyroid carcinoma (n = 3); UCEC, uterine corpus endometrial carcinoma (n = 259; 3). A gray box was drawn to indicate that no normal samples were available for that disease cohort. a mRNASeq profiles obtained for apoA1. b mRNASeq profiles obtained for apoE. RPKM, reads per kilobase million values are indicated