. 2020 Apr 22;12:46. doi: 10.1186/s13195-020-00613-6

Table 2.

Group comparison of EEG characteristics and NBM volume

	HC	AD	LBD	Group comparison
Individual alpha peak	8.8 [8.4, 9.2]	7.4 [6.3, 8.4]	6.4 [6.1, 6.7]	F₂ = 42.1, p < 0.001^a
				p (HC, AD) = 0.004
				p (HC, LBD) < 0.001
				p (AD, LBD) = 0.092
Alpha reactivity	0.56 [0.50, 0.63]	0.24 [0.12, 0.34]	0.08 [0.03, 0.14]	F₂ = 59.9, p < 0.001^b
				p (HC, AD) < 0.001
				p (HC, LBD) < 0.001
				p (AD, LBD) = 0.014
Eyes-closed alpha power	49.1 [41.9, 56.3]	34.4 [27.5, 41.3]	39.7 [35.8, 43.5]	F₂ = 7.9, p = 0.019^a
				p (HC, AD) = 0.018
				p (HC, LBD) = 0.25
				p (AD, LBD) = 0.56
Eyes-open alpha power	18.9 [16.1, 21.7]	24.2 [19.4, 29.0]	36.7 [32.4, 41.1]	F₂ = 35.5, p < 0.001^a
				p (HC, AD) = 0.25
				p (HC, LBD) < 0.001
				p (AD, LBD) = 0.005
NBM volume	0.19 [0.18, 0.20]	0.17 [0.16, 0.17]	0.16 [0.15, 0.17]	F₂ = 13.3, p < 0.001^b
				p (HC, AD) = 0.003
				p (HC, LBD) < 0.001
				p (AD, LBD) = 1.0

Mean [95% confidence interval]. Alpha power and alpha reactivity estimated from electrodes O1, Oz, and O2 using individual alpha peak frequencies. NBM volume normalised to total intracranial volume. Group differences assessed by univariate ANOVA or Kruskal-Wallis ANOVA with post hoc tests corrected for multiple comparisons

AD Alzheimer’s disease, HC healthy controls, LBD Lewy body dementia, NBM nucleus basalis of Meynert

^aKruskal-Wallis ANOVA

^bUnivariate ANOVA