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. 2020 Mar 3;25(5):1134. doi: 10.3390/molecules25051134

Table 3.

Examples of bacteriocins used in food packaging.

Bacteriocin Characteristics Producer Target Microorganisms Ref.
Nisin Heat stable at 121 °C (pH = 2)
Less stable at pH 5–7
Lactobacillus lactis subsp. lactis Streptococcus thermophilus
Lactobacillus spp.
Listeria monocytogenes
Lactobacillus lactis
Staphylococcus aureus
Clostridium botulinum
Bacillus cereus
[43]
Lacticin 3147A Heat stable at 100 °C (10 min at pH 5)
Stable at room and low temperature
Most stable at acid and neutral pH
Lactobacillus lactis DPC3147 Bacillus subtilis
Staphylococcus aureus
Listeria monocytogenes
Lactobacillus fermentum
[44]
Pediocin PA-1 Stable at pH 4 to 6, becomes less stable as pH increases.
Heat stable at 80 °C (10 min)
Pediococcus acidilactici Lactobacillus helveticus
Pediococcus pentosaceus
Listeria monocytogenes
[43]
Enterocin AS-48 Remarkably stable to extremes of pH and denaturing agents
Inactivated by heat at 65 °C and alkaline pH
Compatible with several chemical compounds such as EDTA, lactic acid and sodium hypochlorite
Enterococcus faecalis subsp. liquefaciens S-48 Corynebacterium spp.
Mycobacterium spp.
Nocardia spp.
Micrococcus spp.
Staphylococcus spp.
Listeria monocytogenes
Brochothrix thermosphacta
Lactic acid bacteria
Bacillus cereus
Bacillus coagulans
Bacillus subtilis
Clostridium perfringens
Clostridium sporogenes
Clostridium tetani
Myxococcus spp.
Escherichia coli
Rhizobium spp.
Agrobacterium spp.
Salmonella spp.
Shigella spp.
Pseudomonas spp.
Klebsiella spp.
[45]
Sakacin-A Heat-stable (100 °C, 20 min)
Active at pH 2–9
Most stable at pH 3–5
Stable during frozen storage
Lactobacillus sakei Lb706 Listeria monocytogenes
Listeria innocua
Lactic acid bacteria
[43,46]
Bacteriocin 7293 Stable in organic solvents and high ranges of pH and temperature Weisella hellenica BCC 7293 Pseudomonas aeruginosa
Aeromonas hydrophila
Salmonella Typhimurium
Escherichia coli
[42]