Figure 2.
Effects of SAA on blood glucose and HbA1c in T2DM ZDF rats with AS. ZDF rats were fed with experimental high-fat diets (HFD) for 4 weeks, and were then injected intraperitoneally with 6 × 105 IU/kg of VD3 (three times, every three days). The drugs were administered to the ZDF rats daily, starting after the first VD3 injection for 6 weeks. (A) shows the effects of SAA on blood glucose levels; (B) shows the effects of SAA on blood HbA1c levels. SAA, salvianolic acid A; ATV, atorvastatin. Data are expressed as mean ± SEM, n = 6. * p < 0.05 vs. normal group (Zucker lean control rats); # p < 0.05 vs. model group (Zucker diabetic fatty rats with HFD and VD3 injections).