Figure 3.

Effects of SAA on blood lipid levels in T2DM ZDF rats with AS. ZDF rats were fed with experimental high-fat diets (HFD) for 4 weeks and were then injected intraperitoneally with 6 × 10⁵ IU/kg of VD₃ (three times, every three days). The drugs were administered to the ZDF rats daily, starting after the first VD₃ injection for 6 weeks. The effects of SAA on cholesterol (CHOL) levels (A), triglyceride (TG) levels (B), LDL-C (low density lipoprotein-cholesterol) levels (C) and HDL-C (high density lipoprotein-cholesterol) levels (D) are shown. SAA, salvianolic acid A; ATV, atorvastatin. Data are expressed as mean ± SEM, n = 6. * p < 0.05 vs. normal group (Zucker lean control rats); ^# p < 0.05 vs. model group (Zucker diabetic fatty rats with HFD and VD₃ injections).