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. 2020 Feb 28;25(5):1089. doi: 10.3390/molecules25051089

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of SAA on the expression levels of NLRP3 and caspase-1 in the aortic tissue of T2DM ZDF rats with AS. ZL and ZDF rats were sacrificed, and the aortic tissues were collected for gene and protein expression analysis. The effects of SAA on NLRP3 mRNA (A) and protein (B) expression are shown. (C) The effects of SAA on caspase-1 mRNA expression are shown. Data are expressed as mean ± SEM (n = 6). * p < 0.05 vs. normal group; ^# p < 0.05 vs. model group. (D) Western blotting showed the expression levels of NLRP3 and cleaved caspase-1 protein in each group.