Table 1.
Effects of SAA on insulin resistance and atherosclerosis index in T2DM ZDF rats with AS 1.
| Index | Normal Group | Model Group | ATV Group | SAA Group (0.5 mg/kg) | SAA Group (1 mg/kg) |
|---|---|---|---|---|---|
| HOMA-IR | 4.01 ± 0.42 | 13.18 ± 1.39 * | 9.43 ± 0.66 | 11.72 ± 1.16 | 12.00 ± 0.58 |
| HOMA-IS (×10−3) |
11.87 ± 1.55 | 3.49 ± 0.31 * | 4.51 ± 0.43 | 3.55 ± 0.39 | 3.72 ± 0.19 |
| Atherosclerosis Index | 0.71 ± 0.02 | 6.28 ± 0.32 * | 3.91 ± 0.42 # | 4.30 ± 0.53 # | 4.14 ± 0.61 # |
1 Data are expressed as mean ± SEM (n = 6). * p < 0.05 vs. normal group (Zucker lean control rats). # p < 0.05 vs. model group (Zucker diabetic fatty rats with HFD and VD3 injection).