Scheme 1.
Reagents and conditions: (a) 2 N HCl, MeOH, reflux; (b) (Boc)2O, K2CO3, CH2Cl2; (c) LiAlH4, THF; (d) substituted trans-cinnamic acid, DMAP, EDCI, CH2Cl2; (e) i) CF3COOH, CH2Cl2, ii) HCl-Et2O; (f) KMnO4, 10%H2SO4; (g) 2 N HCl, MeOH.
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