FIG 2.
VIM-1 resistance regions in IncA plasmids identified in this study. A linear map of resistance regions of the 8 IncA plasmids sequenced in this study is shown. Resistance genes are indicated by red-colored arrows, except the blaVIM-1 gene, which is indicated by a turquoise arrow; transposon-related genes (tnpA, tnpR, and tnpM) and class 1 integrase and insertion sequences are indicated by yellow arrows, except the IS26 insertion sequences, which are represented by striped yellow arrows. Other genes are indicated by arrows in the following colors: light green, integration genes identified with respect to pRA1 reference sequence; white, genes trapped within the IS26-blaSHV-12-IS26 element. A bar above the map indicates the IS26-blaSHV-12-blaVIM-1-IS26 module amplified in pGA-VIM, flanked by the two inverted right (IRR) and left (IRL) repeats of IS26.