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Phenotypes of putative FHNA-resistant variants
| Variant | Mean EC50 (μM) ± SD | Fold resistancea |
|---|---|---|
| CHIKV wt | 0.14 ± 0.01 | 1 |
| 1a | 14.10 ± 0.01 | 100 |
| 1b | 3.4 ± 0.6 | 24 |
| 2a | 1.7 ± 0.7 | 12 |
| 2b | 3.0 ± 0.6 | 21 |
| 3 | 1.3 ± 0.8 | 9 |
| 4 | 3.8 ± 0.3 | 27 |
| 5 | 1.8 ± 0.8 | 13 |
The fold resistance = (EC50 variant/EC50 wt).
