. 2020 Mar 24;64(4):e01404-19. doi: 10.1128/AAC.01404-19

TABLE 1.

Antibiotics used in this study

Antibiotic (dose type)	Concn used (μg/ml)	Odds ratio (95% CI)^a	Typical dosage^b	C_max in serum (μg/ml)^b	Half-life (h)^b
Tigecycline (standard)	1	0.91 (0.57–1.45)	100 mg loading, 50 mg q12h, intravenous	0.87	15–44
Tigecycline (high)	20	0.91 (0.57–1.45)	100 mg loading, 50 mg q12h, intravenous	0.87	15–44
Ciprofloxacin (standard)	5	5.65 (4.38–7.28)	400 mg q12h, oral	5.4	3.5–4
Ciprofloxacin (high)	200	5.65 (4.38–7.28)	400 mg q12h, oral	5.4	3.5–4
Clindamycin (standard)	3	20.43 (8.50–49.09)	600 mg q6h, oral	10.8	2
Clindamycin (high)	300	20.43 (8.50–49.09)	600 mg q6h, oral	10.8	2

Values from meta-analysis studies in references 26 and 27. CI, confidence interval.

Values from FDA drug inserts. q12h, every 12 h.