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. 2020 Mar 24;64(4):e01921-19. doi: 10.1128/AAC.01921-19

TABLE 5.

MICs for the active compounds against C. neoformans and C. gattii isolates

Active compound MIC (μg/ml)
C. neoformans strain
C. gattii strain
H99 KN99 CL0741 24067 NIH34 CBS10514 CBS10865 CL4999
Auranofin 4 2 4 2 2 2 2 2
Ciclopirox ethanolamine 0.5 0.5 0.5 0.5 0.5 0.5 0.5 0.5
Clofilium tosylate 32 32 32 32 16 16 16 16
Hycanthone >64 >64 >64 >64 >64 >64 >64 >64
Perphenazine 16 32 32 32 32 16 32 16
Suloctidil 4 4 4 4 4 4 4 4
Tamoxifen 8 8 8 8 8 8 8 8
Thiethylperazine dimalate 32 32 32 32 32 32 32 32
Triclabendazole 8 8 8 8 8 8 8 8
Trifluoperazine dihydrochloride 16 16 16 16 16 16 16 16
Triflupromazine 64 64 32 32 64 32 64 32