TABLE 5.
MICs for the active compounds against C. neoformans and C. gattii isolates
| Active compound | MIC (μg/ml) |
|||||||
|---|---|---|---|---|---|---|---|---|
|
C. neoformans strain |
C. gattii strain |
|||||||
| H99 | KN99 | CL0741 | 24067 | NIH34 | CBS10514 | CBS10865 | CL4999 | |
| Auranofin | 4 | 2 | 4 | 2 | 2 | 2 | 2 | 2 |
| Ciclopirox ethanolamine | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Clofilium tosylate | 32 | 32 | 32 | 32 | 16 | 16 | 16 | 16 |
| Hycanthone | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| Perphenazine | 16 | 32 | 32 | 32 | 32 | 16 | 32 | 16 |
| Suloctidil | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 |
| Tamoxifen | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 |
| Thiethylperazine dimalate | 32 | 32 | 32 | 32 | 32 | 32 | 32 | 32 |
| Triclabendazole | 8 | 8 | 8 | 8 | 8 | 8 | 8 | 8 |
| Trifluoperazine dihydrochloride | 16 | 16 | 16 | 16 | 16 | 16 | 16 | 16 |
| Triflupromazine | 64 | 64 | 32 | 32 | 64 | 32 | 64 | 32 |