TABLE 4.

In vitro chemostat results

^aLog difference at 24 h for each antibiotic alone compared with the control and for each antibiotic combination compared with each antibiotic alone. Synergy and additive effect (≥2-log₁₀ or ≥1-log₁₀ reduction in CFU/ml at 24 h with the combination compared with the most active single drug) are highlighted in orange and green, respectively.

^bThe log difference is presented as the log ratio (LR), which is used to compare any number of log₁₀ CFU of two regimens (test/reference). AUCFU, area under the curve for CFU.