Fig. 2.

Top Row- Microvasculature images: (a) Microvasculature image of a malignant breast lesion after Hessian-based filtering with a minimum size scale of 115.5 μm (equivalent to 3 pixels), and (b) after Hessian-based filtering with a minimum size scale of 423.5 μm (equal to 12 pixels). Both (a) and (b) have a maximum size scale of 500.5 μm (equivalent to 15 pixels). (c) Binary image of (a) (in yellow) with extracted vessel segments (in red). (d) Binary image of (b) (in yellow) with extracted vessel segments (in red). The white ellipse shows an area to identify branches connected to the main vessel trunk. Lower row-Morphological parameters of the lesion as a function of the minimum size scale: (e) Mean of the distance metric [mean(τ)] over different vessel segments. (f) Mean of the diameter of vessel segments [mean(Diameter)]. (g) Mean of the length of vessel segments. (h) Number of vessel segments.