Table 2. Biochemical parameters evaluated in serum samples 24 hours after vehicle, morphine or recombinant Phα1β administrations.
| Treatment | |||||
|---|---|---|---|---|---|
| Vehicle | Morphine | Recombinant toxin (mg/kg i.v.) | |||
| 0.2 | 0.6 | 1.8 | |||
| CK-MB | 73.8 ± 7.6 | 75.1 ± 9.0 | 65.7 ± 10.7 | 75.3 ± 9.0 | 70.4 ± 9.3 |
| TGO | 57.1 ± 2.3 | 47.4 ± 5.0 | 53.7 ± 3.9 | 54.2 ± 4.8 | 55.8 ± 4.4 |
| TGP | 25.0 ± 2.3 | 19.6 ± 1.8 | 21.3 ± 1.7 | 22.1 ± 2.1 | 21.7 ± 2.4 |
| Urea | 72.4 ± 3.8 | 61.6 ± 2.0 | 72.2 ± 6.1 | 69.4 ± 1.2 | 69.7 ± 2.3 |
| Creatinine | 3.7 ± 2.6 | 3.4 ± 0.1 | 3.7 ± 0.2 | 3.6 ± 0.3 | 5.0 ± 1.6 |
| Lactate | 46.9 ± 1.7 | 41.4 ± 1.4 | 42.9 ± 1.6 | 42.0 ± 2.0 | 40.4 ± 1.8 |
| LDH | 637.7 ± 63.8 | 632.0 ± 62.8 | 610.5 ± 55.1 | 624.9 ± 54.2 | 574.6 ± 60.1 |
No statistical significant difference was observed between groups treated with vehicle, morphine (20 mg/kg i.v.) or recombinant Phα1β (0.2 mg/kg i.v.).