Figure 10.

The effects of H. cordata and P. ribesioides extracts on the expression of apoptotic involving proteins in breast cancer cells. MCF-7 and MDA-MB-231 cells were treated with IC20 and IC50 of each ethanolic extract for 24 h, and whole cell lysates were prepared and subjected to Western blotting. The immunoblots were investigated for caspase-7, caspase-8, caspase-9, Bid, tBid, Bcl-xl, BAX and Noxa. β-Actin acted as the loading control. The results are normalized to the control. Data are the means ± SD. * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. control.