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. 2019 Jul 12;152(3):258–276. doi: 10.1093/ajcp/aqz067

Image 4 .

Image 4 

Image 4 

Other neoplasms with germline predisposition syndromes. A, Blasts in acute myeloid leukemia with germline CEBPA mutations often show Auer rods (case 230). Inset, prominent Auer rods. B, Proliferation of large atypical megakaryocytes in essential thrombocythemia with germline SH2B3 mutation (case 42). C, Increased number of mostly normal-appearing megakaryocytes in thrombocytosis with MPL mutation (case 97). D, Sheets of intermediate-sized lymphoid cells in Burkitt lymphoma (case 106) in a patient with X-linked lymphoproliferative disorder. E, Follicular lymphoma, grade 1 to 2 of 3, in a patient with germline TP53 mutation (Li-Fraumeni syndrome; case 209). F, TAFRO (thrombocytopenia, ascites, fibrosis, renal dysfunction, organomegaly), a variant of multicentric Castleman disease (case 200).