Table 6:

Overall and cause-specific survival of adults aged 20 years and older diagnosed with thymus cancer in California by stage at diagnosis, 1988-2015.

Stage at Diagnosis		Overall Survival		Cause-Specific Survival
	First Course of Treatment	HR (95% CI)	P-Value	SHR (95% CI)	P-Value
Localized	No Treatment	Reference		Reference
	Chemotherapy and/or Radiation	1.62 (0.61, 4.26)	0.3303	0.80 (0.15, 4.27)	0.7903
	Surgery Only	0.28 (0.15, 0.53)	0.0001*	0.08 (0.02, 0.30)	0.0002*
	Surgery and Single Modality	0.37 (0.19, 0.72)	0.0038*	0.08 (0.02, 0.34)	0.0008*
	Surgery, Chemotherapy, and Radiation	0.48 (0.18, 1.32)	0.1559	0.97 (0.23, 4.12)	0.9713
Regional	No Treatment	Reference		Reference
	Chemotherapy and/or Radiation	0.58 (0.33, 1.03)	0.0613	0.38 (0.17, 0.89)	0.0260*
	Surgery Only	0.34 (0.19, 0.58)	<0.0001*	0.14 (0.06, 0.34)	<0.0001*
	Surgery and Single Modality	0.34 (0.20, 0.58)	<0.0001*	0.24 (0.11, 0.53)	0.0004*
	Surgery, Chemotherapy, and Radiation	0.42 (0.24, 0.74)	0.0027*	0.30 (0.13, 0.68)	0.0041*
Remote	No Treatment	Reference		Reference
	Chemotherapy and/or Radiation	0.94 (0.62, 1.42)	0.7666	1.40 (0.74, 2.67)	0.2994
	Surgery Only	0.50 (0.27, 0.93)	0.0278*	1.01 (0.41, 2.48)	0.9917
	Surgery and Single Modality	0.43 (0.26, 0.69)	0.0006*	0.65 (0.32, 1.31)	0.2243
	Surgery, Chemotherapy, and Radiation	0.40 (0.24, 0.67)	0.0004*	0.75 (0.37, 1.52)	0.4256

^*Statistically significant

Abbreviations: HR=hazard ratio, SHR=sub-distribution hazard ratio, CI=confidence interval Estimates are adjusted for sex, age at diagnosis, race/ethnicity, neighborhood socioeconomic status, and histology type.