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Antiviral screening data for tilorone generated under the NIAID-DMID NCEA antiviral in vitro screening services
| Virus | Strain | Genus | Type | Cell line | EC50 (μM) | CC50 (μM) | SI |
|---|---|---|---|---|---|---|---|
| CHIK | S27 (VR-67) | Alphavirus | + ssRNAb | Vero 76 | 4.2a | 32 | 7.6 |
| MERS-CoV | EMC | Betacoronavirus | + ssRNA | Vero 76 | 3.7a | 36 | 9.7 |
In vitro antiviral data in Vero 76 cells may underestimate antiviral activity due to lacking interferon pathways.
ssRNA, single-stranded RNA.
