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CZA monotherapy MIC increase and emergence of resistancea
| Initial infection MIC (mg/liter) | Recurrent infection MIC (mg/liter) | Emergence of resistance? | Duration of CZA (days) | Source of infection | Baseline RRT? |
|---|---|---|---|---|---|
| 0.25 | 0.75 | No | 10.6 | Intra-abdominal | No |
| 0.75 | 1.5 | No | 7.6 | Respiratory | No |
| 0.75 | 12 | Yes | 10.3 | Respiratory | Yes |
| 4 | 12 | Yes | 13.2 | Respiratory | Yes |
| 2 | 32 | Yes | 4.4 | Respiratory | Yes |
CZA, ceftazidime-avibactam; RRT, renal replacement therapy.
