TABLE 2.
Treatment |
Cellular concn of DLM metabolites (ng/ml)a
|
||||||
---|---|---|---|---|---|---|---|
NAM-DLM |
NR-DLM |
NAD-DLM |
|||||
Time (h) | IDc | BCG Tokyo | Human hepatocytes | BCG Tokyo | Human hepatocytes | BCG Tokyo | Human hepatocytes |
1 | 1 | 1.52 | <0.104b | 16.0 | <3.35b | 47.8 | <2.65b |
2 | 1.49 | <0.104b | 16.9 | <3.35b | 56.1 | <2.65b | |
Mean | 1.51 | <0.104b | 16.5 | <3.35b | 52.0 | <2.65b | |
24 | 1 | 64.2 | <0.104b | 520 | <3.35b | 170 | <2.65b |
2 | 66.0 | <0.104b | 528 | <3.35b | 194 | <2.65b | |
Mean | 65.1 | <0.104b | 524 | <3.35b | 182 | <2.65b |
The concentrations were measured in duplicate.
Below lower limit of quantification.
ID, measurement number. Mean, mean of 1 and 2.