FIG 2.

Population analysis profiles for NaHCO₃-responsive and nonresponsive strains. (A) Population analysis profiles of CFZ for NaHCO₃-responsive strains in the presence and absence of NaHCO₃. The area under the curve (AUC), calculated by linear approximation, was significantly decreased by exposure to NaHCO₃ in both strains as analyzed by Student’s t test (PB 043-043, ***, P < 0.001; PB 031-038, ****, P < 0.0001). (B) Population analysis profiles of CFZ for NaHCO₃-nonresponsive strains in the presence and absence of NaHCO₃. As analyzed by Student’s t test, there is no significant difference in the AUC for C7 in media ± NaHCO₃; the AUC of RB 067-227 was significantly increased by exposure to NaHCO₃ (*, P < 0.05). (C) Population analysis profiles of CFZ for the methicillin-susceptible S. aureus (MSSA) strain ATCC 25923.