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Effect of JNJ-6379 or ETV on viral particles. HBV-infected PHHs were incubated with compound from day 5, and samples were harvested on day 12. Extracellular and intracellular HBV DNA (Southern blot), HBV core (Western blot), and HBsAg (Western blot) were assessed. DMSO, dimethyl sulfoxide; ETV, entecavir; HBsAg, hepatitis B surface antigen.
