TABLE 2.
MIC, MIEC, and MIEC/MIC ratio of omadacycline and comparators against Legionella pneumophilaa
| Antibiotic | MICb | MIECb,c; MIEC/MIC ratio by: |
|
|---|---|---|---|
| Day 3 of drug exposure | Day 5 of drug exposure | ||
| Omadacycline | 0.25 | 0.12; 0.5 | 0.06; 0.24 |
| Doxycycline | 1 | 0.5; 0.5 | 1; 1 |
| Azithromycin | 0.5 | 0.5; 1 | >0.5; >1 |
| Moxifloxacin | 0.008 | 0.004; 0.5 | 0.004; 0.5 |
a
Five strains were tested (18, 20, 22, ATCC 33152, and 7).
b
Geometric mean value (mg/liter) for MIC and MIEC.
c
MIEC, minimum inhibitory extracellular concentration.