TABLE 1.

Resistance of H. pylori to hydrogen peroxide^a

Generation	MIC (mean ± SE [mg/ml])				MBC (mean ± SE [mg/ml])
	H2O2				Clarithromycin	H2O2				Clarithromycin
	ATCC 43504	Wild type I	Wild type II	Wild type III	ATCC 43504	ATCC 43504	Wild type I	Wild type II	Wild type III	ATCC 43504
0	1.750 ± 0.350	0.650 ± 0.150	1.100 ± 0.500	0.950 ± 0.450	0.003 ± 0.001	2.100 ± 0.700	1.550 ± 0.850	2.050 ± 1.150	2.300 ± 0.900	0.005 ± 0.002
10	2.100 ± 0.400	0.800 ± 0.000	1.550 ± 0.250	1.400 ± 0.000	0.006 ± 0.003	2.950 ± 0.450	2.250 ± 1.250	2.700 ± 1.100	2.600 ± 1.200	0.013 ± 0.005*
20	2.300 ± 0.600	0.800 ± 0.000	2.250 ± 0.950	2.100 ± 0.700	0.013 ± 0.008*	3.500 ± 0.600	3.200 ± 1.800	3.200 ± 1.400	3.000 ± 1.600	0.027 ± 0.009**
30	3.600 ± 0.100**	1.000 ± 0.200	3.150 ± 0.850*	2.350 ± 0.650*	0.032 ± 0.023*	4.700 ± 1.300*	3.700 ± 2.300	4.600 ± 0.900*	3.750 ± 1.750	0.085 ± 0.040**

^aMBC, minimum bactericidal concentration; H₂0₂; hydrogen peroxide; sample number n = 3; generation was defined as a 24-h culture; clarithromycin was a positive control (n = 4). Significance: *, P < 0.05; **, P < 0.01 versus the 0th generation as determined by one-way ANOVA and Student’s t test.