TABLE 4.

Primary endpoint (overall response) definition by infection type^c

Infection type	Time point	Outcome
HABP/VABP	Day 28	All-cause mortality (survival)
cIAI	Day 28	Favorable clinical response (sustained cure or curea )
cUTI	EFU visit	Favorable microbiological response (sustained eradicationb ) and favorable clinical response (sustained cure or curea )

^aAll pretherapy signs and symptoms of the index infection(s) had resolved (or returned to preinfection status), no additional intravenous antibiotic therapy was required, and, for patients with cIAI, no unplanned surgical procedures or percutaneous drainage procedures had been performed (cure was sustained if there was no evidence of a resurgence of the index infection).

^bA culture of urine taken at the EFU visit still showed eradication of the uropathogen found at study entry (i.e., a count of ≥10⁵ CFU/ml was reduced to <10⁴ CFU/ml).

^ccIAI, complicated intra-abdominal infection; cUTI, complicated urinary tract infection; EFU, early follow-up; HABP, hospital-acquired bacterial pneumonia; VABP, ventilator-associated bacterial pneumonia.