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. 2020 Apr 21;64(5):e00261-20. doi: 10.1128/AAC.00261-20

TABLE 1.

C. albicans 5-3 and C. parapsilosis 5-2 demonstrate elevated MICs to MGX and FLC, while C. albicans 5-3 and C. albicans ZCF29/ZCF29W986L are resistant to beauvericin

Background Strain Manogepix
Fluconazole
Beauvericin
MIC (μg/ml) Fold change vs WT MIC (μg/ml) Fold change vs WT MIC (μg/ml) Fold change vs WT
C. albicans ATCC 90028 WT 0.0035 0.125 3.125
5-3 0.014 4 0.5 4 100 32
C. parapsilosis ATCC 22019 WT 0.007 2 25
5-2 0.056 8 4 2 25 1
C. albicans LC191 WT 0.0035 0.125 3.125
ZCF29/ZCF29W986L 0.028 8 0.25 2 100 32