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Scanning electron microscopy of Leishmania amazonensis promastigotes. (A) Control parasites after 72 h of growth; (B, C) 0.5 μM itraconazole (ITZ); (D) 0.5 μM compound 1; and (E, F) 0.5 μM compound 2. Treatment induced significant alterations in the shape of cell bodies; the parasites presented swollen and rounded (B–F), some of them with a long flagellum, sometimes with more than two flagella (B, arrowhead).
