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. 2020 Apr 15;11:466. doi: 10.3389/fphar.2020.00466

Figure 5.

Figure 5

DTT treatment reduces AlCl3-induced oxidative stress in PC12 cells. (A) Intracellular ROS levels from PC12 cells pretreated with DDT for 48 h and AlCl3 induction for 6 h were evaluated by flow cytometry. The bar graph on the right shows the fluorescence intensity of ROS production. (B–E) The effects of DDT on GSH-Px content, CAT, and SOD activities, and MDA content were assessed using biochemical assay kits. Values are means ± standard derivation from three independent experiments. Ctrl: control group. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control group; #p < 0.05, ##p < 0.01, ###p < 0.001 vs. AlCl3-induced model group.