Table 3.
Top 10 Drug-Disease Associations Predicted by CMFMTL.
| Drug name | Disease name | Type | Evidence |
|---|---|---|---|
| Chloroquine | Bradycardia | −1 | Don Michael and Aiwazzadeh, 1970 |
| Chlorpromazine | Coma | −1 | N.A. |
| Risperidone | Anxiety disorders | 1 | Ravindran et al., 2007 |
| Clozapine | Headache | −1 | https://en.wikipedia.org/wiki/Clozapine |
| Methotrexate | Neoplasms | 1 | https://en.wikipedia.org/wiki/Methotrexate |
| Valproic Acid | Fatigue | −1 | N.A. |
| Amitriptyline | Confusion | −1 | https://en.wikipedia.org/wiki/Amitriptyline |
| Ibuprofen | Drug hypersensitivity | −1 | Nanau and Neuman, 2010 |
| Tamoxifen | Diarrhea | −1 | N.A. |
| Vincristine | Neoplasms | 1 | https://en.wikipedia.org/wiki/Vincristine |
N.A. means that the predicted association cannot be confirmed. Type 1 denotes the therapeutic associations and type −1 refers to non-therapeutic associations.