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. 2020 Apr 7;11:531. doi: 10.3389/fmicb.2020.00531

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Copyright © 2020 Bhushan, Lim, Bird, Chothe, Nissly and Kuchipudi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Celgosivir treatment does not inhibit antiviral response in CHME3 cells infected with Zika virus (ZIKV). Relative mRNA expression profiles of MDA5 (A), RIG-I (B), MX1 (C), IRF7 (D), IFNβ (E), and ISG15 (F) of CHME3 cells infected with ZIKV PRVABC59 at 24, 48, and 72 hpi. Data points represent mRNA levels normalized to HPRT1 mRNA for each of three biological replicates. Error bars represent standard error of the mean. Data points with shared letters at the same timepoint have a statistically significant difference (p < 0.05) for the indicated gene.