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. 2020 Apr 7;11:531. doi: 10.3389/fmicb.2020.00531

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Copyright © 2020 Bhushan, Lim, Bird, Chothe, Nissly and Kuchipudi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Iminosugar endoplasmic-reticulum α-glucosidase inhibitor treatment restores cell viability following infection Zika virus (ZIKV) strains IBH30656 or MEX 2-81 in Vero cells. Cell viability at 72 h post infection as measured by MTS assay of castanospermine- (A,B), celgosivir- (C,D), and DNJ- (E,F) treated or vehicle-treated Vero cells infected with ZIKV strain IBH30656 (A,C,E) or MEX 2-81 (B,D,F). Absorbance was measured at 490 nm. Data represents mean absorbance of four biological replicates, with error bars showing standard deviation.