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. Author manuscript; available in PMC: 2020 Apr 23.
Published in final edited form as: Am J Transplant. 2019 Aug 20;20(1):125–136. doi: 10.1111/ajt.15528

TABLE 2.

Design and intervention

Randomization
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Screening Intervention Maintenance
Months 1 2 3 4 5 6 7 8 9 10–15
Intervention group S S S V X X X X X M
MEMS use
 Attention control group S S S V Y Y Y Y Y M
MEMS use

Note: MEMS, Medication Event Monitoring System; S, MEMS use only; at the completion of Month 3, those who were medication adherent exited the study and those with medication nonadherence were randomized; V, In-person visit to begin either SystemCHANGE™ intervention or attention control (patient education) intervention. SystemCHANGE™ teaches patients to use person-level quality improvement strategies to link adherence to established daily routines, environmental cues and supportive people. Attention control (patient education) included discussion of first of 6 transplant health-related brochures; X, Telephone call to receive feedback (MEMS report) and discuss implemented medication adherence solution; Y, telephone call to review transplant-related education materials; M, MEMS use only; at the completion of Month 15, the MEMS were returned and the study was concluded.